clindamycin hydrochloride

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Clindamycin Hydrochloride Special Populations

Number of visits:943 Date:2015/12/14 8:13:58
Clindamycin Hydrochloride Special Populations

Hepatic Impairment

Dosage adjustments not necessary in those with mild or moderate hepatic impairment.

Renal Impairment

Dosage adjustments not necessary in those with mild or moderate renal impairment.

Cautions for Clindamycin Hydrochloride

Clindamycin Hydrochloride Contraindications

Patients hypersensitive to clindamycin or lincomycin.
Warnings/Precautions

Warnings

Superinfection/Clostridium difficile-associated Diarrhea and Colitis (CDAD)

Possible emergence and overgrowth of nonsusceptible bacteria or fungi. Institute appropriate therapy if superinfection occurs.

Treatment with anti-infectives may permit overgrowth of clostridia. Consider CDAD if diarrhea develops and manage accordingly.

Some mild cases of CDAD may respond to discontinuance alone. Manage moderate to severe cases with fluid, electrolyte, and protein supplementation; appropriate anti-infective therapy (e.g., oral metronidazole or vancomycin) recommended if colitis is severe.

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