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Clindamycin Hydrochloride Adults

Number of visits:937 Date:2015/12/7 6:14:49
Clindamycin Hydrochloride Adults


Clindamycin Hydrochloride General Adult Dosage

Serious Infections

Oral
150–300 mg every 6 hours.

IV or IM
600 mg to 1.2 g daily in 2–4 equally divided doses.

More Severe Infections

Oral
300–450 mg every 6 hours.

IV or IM
1.2–2.7 g daily in 2–4 equally divided doses.

For life-threatening infections, dosage may be increased up 4.8 g daily.


Clindamycin Hydrochloride Gynecologic Infections

Pelvic Inflammatory Disease

IV, then Oral
Initially, 900 mg IV every 8 hours; used in conjunction with IV or IM gentamicin. After clinical improvement occurs, discontinue IV clindamycin and gentamicin and switch to oral clindamycin in a dosage of 450 mg 4 times daily to complete 14 days of therapy. Alternatively, oral doxycycline can be used to complete 14 days of therapy.

Pharyngitis and Tonsillitis

Treatment of Symptomatic Patients with Multiple, Recurrent Episodes Known to Caused by Streptococcus pyogenes

Oral
600 mg daily in 2–4 divided doses given for 10 days.122 IDSA states this dosage was not specifically studied in adults and was extrapolated from pediatric dosage recommendation.

Anthrax

Treatment of Inhalational Anthrax?

IV
900 mg every 8 hours.

Used in multiple-drug regimens that initially include IV ciprofloxacin or IV doxycycline and 1 or 2 other anti-infectives predicted to be effective.

Duration of treatment is 60 days if anthrax occurred as the result of exposure to anthrax spores in the context of biologic warfare or bioterrorism.

Babesiosis

Oral

600 mg 3 times daily given for 7–10 days recommended by IDSA and others;104 256 used in conjunction with oral quinine (650 mg every 6–8 hours for 7–10 days).

IV

IDSA recommends 300–600 mg every 6 hours for 7–10 days; used in conjunction with oral quinine (650 mg every 6–8 hours for 7–10 days).256 Others recommend 1.2 g twice daily given for 7–10 days;104 used in conjunction with oral quinine (650 mg 3 times daily for 7–10 days).
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