clindamycin hydrochloride

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clindamycin hydrochloridecurative effects on swine steptococosis

Number of visits:1041 Date:2015/12/3 6:44:32
Study on Stability During Compatibility of Clindamycin Hydrochloride Injection and Vitamin C and Glucose Injection
Objective: To study the stability of the mixed solution of clindamycin hydrochloride injection and vitamin C and glucose injection . Method: The appearance and pH of the compatible solution were observed and the content of clindamycin hydrochloride was determined in 6 hours after they were admixed. Result: There were no obvious differences in appearance and pH after compatibility. The content of clindamycin hydrochloride was kept stable. Conclusion: The two preparations can be kept stable for 6 hours.
The curative effects of clindamycin hydrochloride on swine steptococosis
27 strains of pathogen of swine streptococosis were isolated from three districts in Liaoning province, which were identified as horse Streptococci C group. This MICs of 12 kind of drugs, including clindamycin hydrochloride, to 27 strains Steptococcus were detected with the method of doubling dilution. The MIC_(50) of clindamycin was (0.125) μg/mL. Compared with the pigs in the control group of infection, there were significant difference in death rate, effective rate and curative rate in curing group(P0.01).
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