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clindamycin hydrochloride Identification by TLC

Number of visits:1052 Date:2015/12/3 6:41:09
Identification of lincomycin hydrochloride and clindamycin hydrochloride by TLC
OBJECTIVE A TLC method was developed to separate and identify lincomycin hydrochloride and clindamycin hydrochloride.METHODS The mobile phase was ethyl acetate-acetone-acetic acid-water(10∶5∶2∶2,V/V),After launching and took out air dries and developed with iodine vapor.The coloration spots were brown.RESULTS The chromatographic spots appeared very clearly,and the Rf of lincomycin hydrochloride and clindamyc were 0.38 and 0.57.CONCLUSION The method is reasonable,lincomycin hydrochloride and clindamycin hydrochloride could be separated well
Bacterial Endotoxin Inspection of Clindamycin Hydrochloride Injection
OBJECTIVE The method of bacterial endotoxin inspection of Clindamycin Hydrochloride Injection was discussed.METHODS The interfering action of Clindamycin Hydrochloride Injection and limulus lysate agent from two manufacturers were investigated.RESULTS and CONCLUSIONThe results showed when the sample was diluted 100 times,there would no interference.
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