clindamycin hydrochloride

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Topical clindamycin hydrochloride 1% in acne vulgari

Number of visits:1053 Date:2015/11/30 7:16:32
Topical clindamycin hydrochloride 1% in acne vulgaris
Twenty six patients with moderately severe acne were treated for 12 weeks with topical clindamycin hydrochloride 1% (12 patients) and the vehicle (14 patients). A good or excellent reduction was seen in the non-inflammatory acne lesion count in 3 (25%) of the patients on topical clindamycin and in none of the patients who used the vehicle (control).While 9 (75%) of the patients using topical clindamycin hydrochloride showed a good to excellent response in their inflammatory acne lesion count, only 2 (14.29%) of the control group showed a similar response. The response of the non-inflammatory acne to topical clindamycin hydrochloride 1% was comparable to that of the vehicle, (p> 0.05) while the response of inflammatory acne lesions to topical clindamycin hydrochloride 1% was superior to that of the vehicle (p < 0.05)

The curative effects of clindamycin hydrochloride on dairly acute mastadenitis
The pathogenic bacteria of dairy cattle acute mastitis was isolated and identifyied as Staphylococcus aureus and Streptococcus agalactiae B group. MICs of 12 kinds of drugs, including clindamycin hydrochloricde, to 16 straicns Staphylccoccus aureus and 10 strains Streptococcus agalactiae B group were detected with the method of doubling dilution. The results showed that two kinds of pathogenic bacteria were both sensitve to clindamycin hydrochloride. Compared with the milk cows in the control group of infection, there was very significant difference in cure rate of clindamycin hydrochloride group. It was significant differentces in cure rate and effective ratio of clindamycin hydrochloride group compared with the cows in other drugs鈥 control groups.
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the raw material of clindamycin hydrochloride

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Clindamycin hydrochloride monohydrate and its ethanol solvate
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