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Clindamycin Hydrochloride Uses for Anthrax and Babesiosis

Number of visits:1847 Date:2015/11/27 7:25:30
Clindamycin Hydrochloride Uses for Anthrax

Alternative for treatment of anthrax

Component of multiple-drug parenteral regimens recommended for treatment of inhalational anthrax that occurs as the result of exposure to B. anthracis spores in the context of

biologic warfare or bioterrorism.103 117 119 Initiate treatment with IV ciprofloxacin or doxycycline and 1 or 2 other anti-infective agents predicted to be effective (e.g.,

chloramphenicol, clindamycin, rifampin, vancomycin, clarithromycin, imipenem, penicillin, ampicillin);103 117 if meningitis is established or suspected, use IV ciprofloxacin

(rather than doxycycline) and chloramphenicol, rifampin, or penicillin.

Clindamycin Hydrochloride Uses for Babesiosis

Treatment of babesiosis caused by Babesia microti.

Regimens of choice for babesiosis are clindamycin in conjunction with quinine or atovaquone in conjunction with azithromycin;104 111 144 256 the clindamycin and quinine regimen

may be preferred for severe babesiosis.256 Also consider exchange transfusions in severely ill patients with high levels of parasitemia (>10%), significant hemolysis, or

compromised renal, hepatic, or pulmonary function.
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