clindamycin hydrochloride

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Clindamycin Hydrochloride CapsulesⅠ

Number of visits:1010 Date:2015/12/25 1:44:48
Ingredients:
Clindamycin hydrochloride
Indications:
Clindamycin hydrochloride capsules  is used for streptococcus, staphylococcus aureus and anaerobic bacteria and other sensitive strain caused by the following infection: otitis media, sinusitis, suppurative tonsillitis, pneumonia; Skin soft tissue infection; In the treatment of bone and joint infection, abdominal cavity infection, pelvic infection, pyothorax, lung abscess, osteomyelitis, sepsis, etc., according to the situation or combine with other joint application of antimicrobials.

Usage and dosage:
Adults, a 0.15 ~ 0.3g, 4 times a day orally, severe infection can be increased to 0.45g, 4 times a day. 4 weeks or 4 weeks or more children, 1 8 to 16mg/kg in weight, 3 ~ 4 times.

Taboo:
It is forbidden of clindamycin and clindamycin disabled patients with a history of allergies.

Note:
(1) patients with allergic to clindamycin that may also allergic to clindamycin.
(2) to the diagnosis of interference: medication after serum alanine aminotransferase and nmda amino transferase can be increased.
(3) should be careful in the following circumstances:
①intestinal disease or have a past medical history, special limitations such as ulcerative colitis, inflammatory bowel disease or antibiotics related enteritis;
②liver function impairment; 
③renal severe impairment.
(4) to prevent the occurrence of acute rheumatic fever, treatment with clindamycin hemolytic streptococcus infection treatment, at least for 10 days.
(5) during the medication should pay close attention to defecate frequency, such as occurrence defecate number increase, we should pay attention to the possibility of false membranous enteritis, stop drug must be timely and appropriate processing.
(6) it is the result of clindamycin membrane enteritis, mild withdrawal could effectively alone, moderate to severe patients need to correct water and electrolyte disturbances. As it is the above treatment, no obvious improvement, should give metronidazole oral 250 ~ 250 mg, three times a day. When such as recurrence, reusable metronidazole oral, still is invalid when switching to vancomycin (or to a vancomycin) oral, adult every day 0.5 ~ 2.0g, 3 ~ 4times.
(7) patients with decreased renal function (unless severe impairment), are generally not required at dosage of this product. Patients with severe renal and liver function impairment, when using this product should be serum drug concentration monitoring.
(8) this product can cause excessive proliferation, this product is not sensitive microbes especially fungi, so must be noticed when applying second infection.

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